Descriptions of passenger lymphocyte syndrome (PLS), immune cytopenias and transplant-associated thrombotic microangiopathy (TA-TMA) after intestine-containing transplants remain scarce.
Read MoreCharlotte S Rutter 1, Neil K Russell 2, Lisa M Sharkey 1, Irum Amin 2, Andrew J Butler 3 Affiliations expand PMID: 33565629 DOI: 10.1111/ctr.14249 Abstract Introduction: This study reports the incidence of chronic kidney disease (CKD) after intestinal transplant (IT) at a single, adult center in the United Kingdom. Methods: A retrospective review of IT was undertaken. Methods of renal function assessment pre-transplant were compared. Post-transplant renal function…
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Darren Wong 1 2, William Thomas 3, Andrew Butler 4, Lisa Sharkey 5 Affiliations expand PMID: 33980556 PMCID: PMC8118027 (available on 2023-05-12) DOI: 10.1136/bcr-2021-241634 Abstract A 25-year-old man who received alemtuzumab as induction therapy for a multivisceral transplant experienced delayed onset of warm autoimmune haemolytic anaemia and neutropaenia. Serological testing and bone marrow biopsy excluded alternative causes. Haemolysis was refractory to standard therapies including corticosteroids, intravenous immunoglobulin and rituximab.…
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P J Allan 1, T Ambrose 1, C Mountford 2, A Bond 3, C Donnellan 4, R Boyle 5, C Calvert 6, E Cernat 7, E Clarke 8, S C Cooper 9, S Donnelly 10, B Evans 11, M Glynn 12, R Hewett 13, A S Holohan 14, E F Leitch 15, J Louis-Auguste 16, S Mehta 17, S Naik 18, J Nightingale 19, G Rafferty 20, A Rodrigues 21, L Sharkey 22, M Small 10, A Teubner 23, A Urs 24, N Wyer 25, S Lal 23 26 Affiliations expand PMID: 33586170 PMCID: PMC8013499 DOI: 10.1002/jpen.2087 Abstract Background: The direct effect of the coronavirus disease 2019 (COVID-19) pandemic on patients with intestinal failure (IF) has…
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The Long and Short of IT: intestinal failure-associated liver disease (IFALD) in adults-recommendations for early diagnosis and intestinal transplantation Jeremy Mark Woodward 1, Dunecan Massey 1, Lisa Sharkey 1 Affiliations expand PMID: 31885838 PMCID: PMC6914300 DOI: 10.1136/flgastro-2018-101069 Abstract Intestinal failure-associated liver disease (IFALD) often presents in adults unexpectedly with advanced disease. Non-invasive tests can be falsely reassuring. Patients with ‘ultrashort’ intestine (<20 cm) ending…
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John R Louis-Auguste 1, Christianne Micallef 2, Tim Ambrose 3, Sara Upponi 4, Andrew J Butler 5, Dunecan Massey 3, Stephen J Middleton 3, Neil Russell 5, Charlotte S Rutter 6, Lisa M Sharkey 3, Jeremy Woodward 3, Effrossyni Gkrania-Klotsas 7, David A Enoch 2 Affiliations expand PMID: 29942755 PMCID: PMC6010962 DOI: 10.1016/j.idcr.2018.03.017 Free PMC article Abstract Introduction: Antifungal agents are routinely used in the post-transplant setting for both prophylaxis and treatment of presumed and proven fungal infections. Micafungin is an echinocandin-class antifungal with broad…
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